Milbemycin oxime with Lufenuron is used in the prevention of heartworm disease and in the control of hookworm, roundworm and whipworm. When combined with Lufenuron it is also used to control fleas by preventing the development of flea eggs. The medication does not kill adult fleas.

Manufactured by Novartis

Milbemycin oxime with Lufenuron is indicated for use in dogs and puppies four weeks of age and older, and two pounds body weight or greater. The usual dose of milbemycin oxime with Lufenuron for dogs 2-10 pounds is 2.3mg/46mg, 11-25 pounds is 5.75mg/115mg, 26-50 pounds is 11.5mg/230mg and 51-100 pounds is 23mg/460mg given once a month year round. An alternate treatment is to give this medication once a month during the mosquito season and also one month after the season ends.

This medication should not be used in animals allergic to it. The pet should be tested for heartworm disease before starting this medication. If the pet has been off heartworm preventative for 6 months or more, retest in 6 months since microfilaria, that take 6 months to mature, will cause a positive test result. Because humans can contract hookworm and roundworm from animals it is important to maintain good personal hygiene. It is also important to eliminate fleas on the pet and in the household and to not feed the pet rodents or uncooked meat or fish. To prevent reinfection, daily cleanup of stools is recommended.

Milbemycin oxime/lufeneron